Biased Ligands. Better Drugs.

TRV027 in-vitro and in-vivo pharmacology summary

TRV120027, a Beta-arrestin biased ligand at the angiotensin II type 1 receptor, produces unique pharmacology and is a novel potential therapy for heart failure. Presented at the 2010 Heart Failure of Society of America meeting

Violin JD, Soergel DG, DeWire SD, Yamashita D, Rominger D, Whalen EJ, Gowen M, Lark MW.

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