EX-23.1
Published on March 18, 2015
QuickLinks -- Click here to rapidly navigate through this document
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the Registration Statements on Form S-8 (No. 333-193735 and 333-201672) of our report dated March 18, 2015, with respect to the financial statements of Trevena, Inc. included in this Annual Report on Form 10-K for the year ended December 31, 2014.
| /s/ Ernst & Young LLP |
Philadelphia,
Pennsylvania
March 18, 2015
Consent of Independent Registered Public Accounting Firm