Form: 10-K

Annual report pursuant to Section 13 and 15(d)

March 9, 2016


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Exhibit 12.1

TREVENA, INC.
COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES

 
  2011   2012   2013   2014   2015  

Determination of earnings

                               

Income/(loss) before income taxes

  $ (15,810,004 ) $ (15,635,658 ) $ (23,251,435 ) $ (49,700,875 ) $ (50,528,240 )

Add:

                               

Fixed Charges

    215,036     339,798     302,852     233,920     530,952  

Total Earnings/(loss)

    (15,594,968 )   (15,295,860 )   (22,948,583 )   (49,466,955 )   (49,997,288 )

Fixed charges:

                               

Interest expense and amortization of debt discount and deferred financing costs

    74,217     193,740     149,756     70,650     334,365  

Estimated interest component of rent expense

    140,819     146,058     153,096     163,270     196,587  

Total fixed charges

    215,036     339,798     302,852     233,920     530,952  

Ratio of earnings to fixed charges(1)

                               

Deficiency of earnings to cover fixed charges

  $ 15,810,004   $ 15,635,658   $ 23,251,435   $ 49,700,875   $ 50,528,240  

(1)
For all periods presented, no ratios are provided as earnings were insufficient to cover fixed charges.



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TREVENA, INC. COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES