Quarterly report pursuant to Section 13 or 15(d)

Stockholders' Equity - Options Outstanding (Details)

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Stockholders' Equity - Options Outstanding (Details) - $ / shares
3 Months Ended 12 Months Ended
Mar. 31, 2022
Dec. 31, 2021
Number of Shares    
Balance at the beginning of the period (in shares) 12,449,870  
Granted (in shares) 244,950  
Forfeited/Cancelled (in shares) (435,809)  
Balance at the end of the period (in shares) 12,259,011 12,449,870
Vested or expected to vest at the end of the period (in shares) 12,259,011  
Exercisable at the end of the period (in shares) 7,457,237  
Weighted-Average Exercise Price    
Balance at the beginning of the period (in dollars per share) $ 2.67  
Granted (in dollars per share) 0.60  
Forfeited/Cancelled (in dollars per share) 1.85  
Balance at the end of the period (in dollars per share) 2.65 $ 2.67
Vested or expected to vest at the end of the period (in dollars per share) 2.65  
Exercisable at the end of the period (in dollars per share) 3.30  
Closing price of Company's stock (in dollars per share) $ 0.55  
Weighted Average Remaining Contractual Term    
Options Outstanding at the end of the period 6 years 11 months 19 days 7 years 1 month 9 days
Vested or expected to vest at the end of the period 6 years 11 months 19 days  
Exercisable at the end of the period 5 years 7 months 28 days