Quarterly report pursuant to Section 13 or 15(d)

Stockholder's Equity - Shares Reserved for Future Grant and Issuance (Details)

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Stockholder's Equity - Shares Reserved for Future Grant and Issuance (Details) - shares
9 Months Ended
Sep. 30, 2021
Dec. 31, 2020
Shares Reserved for Future Issuance    
Stock options outstanding (in shares) 11,553,876 9,564,519
Warrants outstanding (in shares) 295,591  
Total shares of common stock reserved for issuance (in shares) 24,322,862  
2013 plan    
Shares Available for Future Grant    
Balance at the beginning of the period (in shares) 4,053,501  
Authorized (in shares) 6,399,997  
Granted (in shares) (2,685,142)  
Shares withheld for taxes not issued 49,915  
Forfeited/Cancelled (in shares) 1,145,801  
Balance at the end of the period (in shares) 8,964,072  
Shares Reserved for Future Issuance    
Shares available for future grant (in shares) 8,964,072 4,053,501
Inducement Plan    
Shares Available for Future Grant    
Balance at the beginning of the period (in shares) 252,500  
Balance at the end of the period (in shares) 252,500  
Shares Reserved for Future Issuance    
Shares available for future grant (in shares) 252,500 252,500
2013 Employee Stock Purchase Plan    
Shares Reserved for Future Issuance    
Total shares of common stock reserved for issuance (in shares) 225,806  
Employee Stock Option | 2013 plan    
Shares Reserved for Future Issuance    
Stock options outstanding (in shares) 11,306,376  
Employee Stock Option | Inducement Plan    
Shares Reserved for Future Issuance    
Stock options outstanding (in shares) 247,500  
Restricted Stock Units | 2013 plan    
Shares Reserved for Future Issuance    
Total shares of common stock reserved for issuance (in shares) 3,031,017