| Schedule of share-based compensation expense recognized |
|
|
|
Year Ended
December 31,
|
|
|
|
|
2014
|
|
2013
|
|
|
Research and development
|
|
$
|
1,129,244
|
|
$
|
609,483
|
|
|
General and administrative
|
|
|
1,254,155
|
|
|
318,513
|
|
|
|
|
|
|
|
|
|
|
|
Total stock-based compensation
|
|
$
|
2,383,399
|
|
$
|
927,996
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Schedule of options outstanding |
|
|
|
|
|
Options Outstanding
|
|
|
|
|
Shares
Available
for Grant
|
|
Number
of Shares
|
|
Weighted-
Average
Exercise
Price
|
|
Weighted
Average
Remaining
Contractual
Term (in years)
|
|
|
Balance, December 31, 2012
|
|
|
171,803
|
|
|
1,523,156
|
|
$
|
0.56
|
|
|
7.89
|
|
|
Authorized
|
|
|
1,459,514
|
|
|
—
|
|
|
|
|
|
|
|
|
Granted
|
|
|
(1,730,156
|
)
|
|
1,730,156
|
|
|
3.73
|
|
|
|
|
|
Exercised
|
|
|
—
|
|
|
(275,262
|
)
|
|
0.30
|
|
|
|
|
|
Forfeitures
|
|
|
182,304
|
|
|
(182,304
|
)
|
|
0.95
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Balance, December 31, 2013
|
|
|
83,465
|
|
|
2,795,746
|
|
$
|
2.52
|
|
|
8.45
|
|
|
Authorized
|
|
|
1,711,290
|
|
|
—
|
|
|
|
|
|
|
|
|
Granted
|
|
|
(1,095,042
|
)
|
|
1,095,042
|
|
|
6.75
|
|
|
|
|
|
Exercised
|
|
|
—
|
|
|
(186,687
|
)
|
|
0.60
|
|
|
|
|
|
Forfeitures
|
|
|
129,651
|
|
|
(129,651
|
)
|
|
7.20
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Balance, December 31, 2014
|
|
|
829,364
|
|
|
3,574,450
|
|
$
|
3.75
|
|
|
8.06
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Vested or expected to vest at December 31, 2014
|
|
|
|
|
|
3,528,809
|
|
$
|
3.71
|
|
|
8.05
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Exercisable at December 31, 2014
|
|
|
|
|
|
1,602,623
|
|
$
|
2.26
|
|
|
7.10
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Schedule of shares of common stock reserved for issuance |
|
Common stock options outstanding
|
|
|
3,574,450
|
|
|
Common stock options and restricted stock available for future grant (2013 Plan)
|
|
|
829,364
|
|
|
Common stock warrants outstanding
|
|
|
30,258
|
|
|
|
|
|
|
|
|
|
|
|
4,434,072
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|