Income Taxes - Deferred Taxes (Details) - USD ($) |
12 Months Ended | |
|---|---|---|
Dec. 31, 2015 |
Dec. 31, 2014 |
|
| Income Taxes | ||
| Net loss before income taxes | $ 50,528,240 | $ 49,700,875 |
| Deferred tax assets: | ||
| Net operating loss carryforwards | 11,649,441 | 9,245,934 |
| Research and development credits | 6,824,974 | 5,101,755 |
| Research and development expenses capitalized for tax purposes | 61,073,917 | 43,038,057 |
| Deferred rent | 103,454 | 129,998 |
| Depreciation | 552,235 | 476,799 |
| Other temporary differences | 653,078 | 458,413 |
| Total deferred tax assets | 80,857,099 | 58,450,956 |
| Deferred tax liabilities: | ||
| Prepaid expenses | (81,706) | (90,385) |
| Total deferred tax liabilities | (81,706) | (90,385) |
| Net deferred tax assets | 80,775,393 | 58,360,571 |
| Less valuation allowance | (80,775,393) | (58,360,571) |
| Increase in valuation allowance | $ 22,400,000 | $ 22,100,000 |
| X | ||||||||||
- Definition Represents the amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards, net of deferred tax liability attributable to taxable temporary differences. No definition available.
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- Definition Represents the amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from research and development expenses capitalized for tax purposes. No definition available.
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- Definition Amount of deferred tax liability attributable to taxable temporary differences. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- References No definition available.
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences not separately disclosed. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from property, plant, and equipment. No definition available.
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible research tax credit carryforwards. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from deferred rent. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- References No definition available.
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| X | ||||||||||
- Definition Amount of deferred tax consequences attributable to taxable temporary differences derived from prepaid expenses. No definition available.
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- References No definition available.
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Amount of increase (decrease) in the valuation allowance for a specified deferred tax asset. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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